Cytokines production by effector memory CD4⁺ T cells from LTBI and BCG individuals.

<p>(A) Functional profile of IFN-γ, IL-2 and TNF-α CD4⁺ T cells are shown in representative LTBI and BCG individuals. (B) Polyfunctional cytokine production by memory CD4⁺ T cells from LTBI and BCG. Data are represented as the mean percentage of responding CD4⁺ T cells that are triple producers (3+), double producers (2+) or single producers (1+) of IFN-γ, TNF-α, and IL-2 and summarized by the pie charts. Each slice of the pie represents the fractions of the total response that consists of CD4⁺ T cells positive for a given function.