HSA/TIMP-2 inhibits tumor cell proliferation but not apoptosis in prostate tumors.

<p>(A) Representative immunohistochemical images of Ki-67 and active caspase-3 immunohistochemistry. Tumor sections were obtained at 15 days after initial injection of 80 mg/kg HSA/TIMP-2 (<i>n</i> = 4 per group). The representative images were taken at an original magnification of 200×. (B) Quantification of Ki67- and active caspase-3-positive cells as expressed by the percentage of brown pixels per field. The quantitative data represent the mean ± SEM (<i>n</i> = 4 per group). Significant difference compared to the control group: ^*<i>P</i><0.05 by Student's <i>t</i> test. <i>ns</i> = non-significant.