<p>Sections from P7 wild type (A, C–D) or GFAP:Hi-Otx2 (B, E–J) mice were immunostained with the indicated antibodies. For (A) and (B), anterior expression threshold is designated with a red arrow. (A, B) are shown at 4× magnification (mag), all others 20× mag. sc, superior colliculus; egl, external granule layer; igl, internal granule layer. White arrows indicate overlapping expression of the indicated markers in individual cells.</p
<p>(A, C, E) Immunofluorescent staining for Pax6 in (A) wild type cerebellum, (C) GFAP:Hi-Otx2 cereb...
(A) The set of putative Otx2 target genes, previously identified by expression analysis in Otx2-abla...
<p>(A) Luciferase assay for enhancer activity of DHS 4 in OTX2-expressing medulloblastoma cells trea...
International audienceBackground Dynamic monitoring of protein expression and localization is fundam...
<p><b>A.</b> Experimental design: four independent ChIP experiments were performed. RPE and neural r...
<p>(A–F) H & E stained sections from P7 hindbrains of (A, C, E) wild type and (B, D, F) GFAP:Hi-Otx2...
<div><p>During postnatal life the cerebral cortex passes through critical periods of plasticity allo...
Plasticity in the visual cerebral cortex is regulated by the internalization of Otx2 homeoprotein in...
<p>(A) Protein expression of OTX2, OTX2L and OTX2S was detected by western blot analysis using polyc...
The Otx2 homeodomain transcription factor is essential for gastrulation and early neural development...
The Otx2 homeoprotein transcription factor is expressed in the dopaminergic neurons of the ventral t...
International audienceOTX2 is a homeoprotein transcription factor expressed in photoreceptors and bi...
<p>Images of H & E stained sections (20× mag) from (A) wild type mice, (B) GFAP:Hi-Otx2 mice, and (C...
<p>Retroviral particles expressing EGFP or Gsx2-EGFP were injected into the OB SEZ of P4 mice, and O...
International audienceThe non-cell autonomous transfer of OTX2 homeoprotein transcription factor int...
<p>(A, C, E) Immunofluorescent staining for Pax6 in (A) wild type cerebellum, (C) GFAP:Hi-Otx2 cereb...
(A) The set of putative Otx2 target genes, previously identified by expression analysis in Otx2-abla...
<p>(A) Luciferase assay for enhancer activity of DHS 4 in OTX2-expressing medulloblastoma cells trea...
International audienceBackground Dynamic monitoring of protein expression and localization is fundam...
<p><b>A.</b> Experimental design: four independent ChIP experiments were performed. RPE and neural r...
<p>(A–F) H & E stained sections from P7 hindbrains of (A, C, E) wild type and (B, D, F) GFAP:Hi-Otx2...
<div><p>During postnatal life the cerebral cortex passes through critical periods of plasticity allo...
Plasticity in the visual cerebral cortex is regulated by the internalization of Otx2 homeoprotein in...
<p>(A) Protein expression of OTX2, OTX2L and OTX2S was detected by western blot analysis using polyc...
The Otx2 homeodomain transcription factor is essential for gastrulation and early neural development...
The Otx2 homeoprotein transcription factor is expressed in the dopaminergic neurons of the ventral t...
International audienceOTX2 is a homeoprotein transcription factor expressed in photoreceptors and bi...
<p>Images of H & E stained sections (20× mag) from (A) wild type mice, (B) GFAP:Hi-Otx2 mice, and (C...
<p>Retroviral particles expressing EGFP or Gsx2-EGFP were injected into the OB SEZ of P4 mice, and O...
International audienceThe non-cell autonomous transfer of OTX2 homeoprotein transcription factor int...
<p>(A, C, E) Immunofluorescent staining for Pax6 in (A) wild type cerebellum, (C) GFAP:Hi-Otx2 cereb...
(A) The set of putative Otx2 target genes, previously identified by expression analysis in Otx2-abla...
<p>(A) Luciferase assay for enhancer activity of DHS 4 in OTX2-expressing medulloblastoma cells trea...