1<p>Number of beads counted for a specific sequence string in a total of 500,000 beads. The “0” in the sequence string represents an empty position for which only background florescence was recorded. Beads positives for more than one allele (two alleles per SNP) derived from multi-template reactions were removed from the data.</p>2<p>Ratio of alleles obtained for heterozygous DNA.</p>3<p>Sum of beads informative for the queried SNPs relative to the total number of beads with a product. The sum of different types of drop-outs (“0” in sequence string) are shown for the multiplex reactions.</p
Allelic association studies provide the most powerful method for locating genes of small effect cont...
In certain crime cases, information about a perpetrator's phenotype, including eye colour, may be a ...
Large samples and systematic screens of thousands of DNA markers are needed to detect quantitative t...
<p>In step 1, a region of several kilobases containing several polymorphic sites is amplified from g...
Abstract Background DNA pooling is a technique to reduce genotyping effort while incurring only mino...
<p>A genomic DNA sample is emulsified into aqueous droplets in an oil-aqueous reverse emulsion. Alle...
In DNA pooling study, the κ correction method is often carried out to adjust the unequal amplificati...
The amplification of millions of single molecules in parallel can be performed on microscopic magnet...
Haplotypes derived by single molecule sequencing using emulsion PCR. Samples are from populations of...
Several groups have developed methods for estimating allele frequencies in DNA pools as a fast and c...
Advances in high throughput screening (HTS), together with the rapid progress in combinatorial chemi...
In the effort to become the first to establish the “thousand dollar genome,” a fundamental component...
Detecting rare sequence variants in genomic DNA is central to the analysis of de novo mutation and r...
Background: One of the major obstacles to the exploitation of genetic variation in human medicine, v...
Large samples and systematic screens of thousands of DNA markers are needed to detect quantitative t...
Allelic association studies provide the most powerful method for locating genes of small effect cont...
In certain crime cases, information about a perpetrator's phenotype, including eye colour, may be a ...
Large samples and systematic screens of thousands of DNA markers are needed to detect quantitative t...
<p>In step 1, a region of several kilobases containing several polymorphic sites is amplified from g...
Abstract Background DNA pooling is a technique to reduce genotyping effort while incurring only mino...
<p>A genomic DNA sample is emulsified into aqueous droplets in an oil-aqueous reverse emulsion. Alle...
In DNA pooling study, the κ correction method is often carried out to adjust the unequal amplificati...
The amplification of millions of single molecules in parallel can be performed on microscopic magnet...
Haplotypes derived by single molecule sequencing using emulsion PCR. Samples are from populations of...
Several groups have developed methods for estimating allele frequencies in DNA pools as a fast and c...
Advances in high throughput screening (HTS), together with the rapid progress in combinatorial chemi...
In the effort to become the first to establish the “thousand dollar genome,” a fundamental component...
Detecting rare sequence variants in genomic DNA is central to the analysis of de novo mutation and r...
Background: One of the major obstacles to the exploitation of genetic variation in human medicine, v...
Large samples and systematic screens of thousands of DNA markers are needed to detect quantitative t...
Allelic association studies provide the most powerful method for locating genes of small effect cont...
In certain crime cases, information about a perpetrator's phenotype, including eye colour, may be a ...
Large samples and systematic screens of thousands of DNA markers are needed to detect quantitative t...