Sublethal doses of SYN876 suppress aldicarb effects.

<p>Wild-type <i>C. elegans</i> was exposed to the indicated compound concentrations. Worms exposed to 1 mM aldicarb are hypercontracted and exhibit little movement (lower left panel). In the presence of both 1 mM aldicarb and 1 µg.ml^-1 SYN876 the worms are much less hypercontracted and exhibit fairly normal sinusoidal locomotion (arrow, lower right panel). Worms exposed to 1 mM aldicarb and <u>></u>2.5 µg/ml SYN876 exhibit movement and growth defects similar to those induced by SYN876 alone (uncoordinated movement and coiling without hypercontraction; not shown).