<p>(A) T-lymphocytes infiltrating injured (right) and uninjured (left) hemisphere, visualized by anti-CD3 immunohistochemistry. Ruler indicates 200 µm. (B) CD4<sup>+</sup> (left) and CD8<sup>+</sup> (right) T-lymphocyte infiltrating cells per 10<sup>6</sup> live cells after HI brain injury (C) the expression of the naïvety marker CD45rb, and (D) the activation markers CD69 and CD25 in these populations. Open red circle = infarcted hemisphere, black triangle = uninjured hemisphere, blue square = sham operated and green filled circle = unoperated.</p
Background and purposeAutoimmune responses can occur when antigens from the central nervous system a...
Background and Purpose-Autoimmune responses can occur when antigens from the central nervous system ...
Pathology of the nervous system is related to different immune processes: destructive changes in tis...
<p>(A) Temporal correlation of activated cells after HI brain injury. Note the 24 h and one week act...
<p>(A) CD4<sup>+</sup> and CD8<sup>+</sup> T-lymphocytes in unoperated age matched control (left) an...
<p>(A) Time-line with experimental setup. (B) Representative cross-section of MAP-2 (live neurons) s...
<div><h3>Background</h3><p>Hypoxic ischemia (HI) is an important cause of neonatal brain injury and ...
<p>A: Dot plots of isolated immune cells in the brain, gated for live cell analysis. B: Representati...
<p>(A) Proliferation index of splenocytes from mice three and five months after HI or sham operation...
<p>Example control images obtained with a 20x objective, the magnification used for cell counting (s...
Background: Evidence suggests that brain infiltration of lymphocytes contributes to acute neural inj...
<p>A: Dot plots of isolated immune cells in the brain, gated for live cell analysis. B: Representati...
Tissues were collected as described in the legend for Fig 10. The specific markers used to distingui...
Immune cells display a high degree of phenotypic plasticity, which may facilitate their participatio...
Background: Traumatic injury to the central nervous system (CNS) triggers a robust inflammatory resp...
Background and purposeAutoimmune responses can occur when antigens from the central nervous system a...
Background and Purpose-Autoimmune responses can occur when antigens from the central nervous system ...
Pathology of the nervous system is related to different immune processes: destructive changes in tis...
<p>(A) Temporal correlation of activated cells after HI brain injury. Note the 24 h and one week act...
<p>(A) CD4<sup>+</sup> and CD8<sup>+</sup> T-lymphocytes in unoperated age matched control (left) an...
<p>(A) Time-line with experimental setup. (B) Representative cross-section of MAP-2 (live neurons) s...
<div><h3>Background</h3><p>Hypoxic ischemia (HI) is an important cause of neonatal brain injury and ...
<p>A: Dot plots of isolated immune cells in the brain, gated for live cell analysis. B: Representati...
<p>(A) Proliferation index of splenocytes from mice three and five months after HI or sham operation...
<p>Example control images obtained with a 20x objective, the magnification used for cell counting (s...
Background: Evidence suggests that brain infiltration of lymphocytes contributes to acute neural inj...
<p>A: Dot plots of isolated immune cells in the brain, gated for live cell analysis. B: Representati...
Tissues were collected as described in the legend for Fig 10. The specific markers used to distingui...
Immune cells display a high degree of phenotypic plasticity, which may facilitate their participatio...
Background: Traumatic injury to the central nervous system (CNS) triggers a robust inflammatory resp...
Background and purposeAutoimmune responses can occur when antigens from the central nervous system a...
Background and Purpose-Autoimmune responses can occur when antigens from the central nervous system ...
Pathology of the nervous system is related to different immune processes: destructive changes in tis...