<p>(A) CD4<sup>+</sup> and CD8<sup>+</sup> T-lymphocytes in unoperated age matched control (left) and damaged brain hemisphere (right) two weeks after HI. Note the double positive population marked in red. (B) Proportion CD4<sup>+</sup>CD8<sup>+</sup> double positive T-lymphocytes in brain and (C) spleen after HI. Red circle = infarcted hemisphere (B) or HI (C), black triangle = uninjured hemisphere, blue diamond = sham operated, and green square = unoperated.</p
<p>T cells (CD3<sup>+</sup> cells) were immunostained and counted (absolute number, n) in coronal sl...
<div><h3>Background</h3><p>Hypoxic ischemia (HI) is an important cause of neonatal brain injury and ...
(A) Representative histogram of CD103+ and CD103- DbLT359 tetramer+ CD8 T cells from brain and splee...
<p>(A) T-lymphocytes infiltrating injured (right) and uninjured (left) hemisphere, visualized by ant...
<p>(A) Temporal correlation of activated cells after HI brain injury. Note the 24 h and one week act...
Pathology of the nervous system is related to different immune processes: destructive changes in tis...
<p><b>(A–B)</b> Upper panel shows representative triple-labeled immunostaining of CD8+CD68+ cells ex...
Background and Purpose—Cerebral ischemia is ensued by a cellular immune depression syndrome. The pos...
<p>A: Dot plots of isolated immune cells in the brain, gated for live cell analysis. B: Representati...
(A) Experimental design. (B) Number of CD4 T cells in brain. (C) Number of virus-specific CD8 T cell...
<p>(A) Time-line with experimental setup. (B) Representative cross-section of MAP-2 (live neurons) s...
<p>A, B) Influx of CD4<sup>+</sup> and CD8<sup>+</sup> tumor infiltrating lymphocytes respectively w...
(A) Flow plots and (B) bar graphs show CCR5 expression on CD4+CD95+ T cells in controls, second bar ...
Tissues were collected as described in the legend for Fig 10. The specific markers used to distingui...
(A, B) Number (left) and frequency (right) of CD44hi DbLT359 tetramer+ CD8 T cells in brain (A) and ...
<p>T cells (CD3<sup>+</sup> cells) were immunostained and counted (absolute number, n) in coronal sl...
<div><h3>Background</h3><p>Hypoxic ischemia (HI) is an important cause of neonatal brain injury and ...
(A) Representative histogram of CD103+ and CD103- DbLT359 tetramer+ CD8 T cells from brain and splee...
<p>(A) T-lymphocytes infiltrating injured (right) and uninjured (left) hemisphere, visualized by ant...
<p>(A) Temporal correlation of activated cells after HI brain injury. Note the 24 h and one week act...
Pathology of the nervous system is related to different immune processes: destructive changes in tis...
<p><b>(A–B)</b> Upper panel shows representative triple-labeled immunostaining of CD8+CD68+ cells ex...
Background and Purpose—Cerebral ischemia is ensued by a cellular immune depression syndrome. The pos...
<p>A: Dot plots of isolated immune cells in the brain, gated for live cell analysis. B: Representati...
(A) Experimental design. (B) Number of CD4 T cells in brain. (C) Number of virus-specific CD8 T cell...
<p>(A) Time-line with experimental setup. (B) Representative cross-section of MAP-2 (live neurons) s...
<p>A, B) Influx of CD4<sup>+</sup> and CD8<sup>+</sup> tumor infiltrating lymphocytes respectively w...
(A) Flow plots and (B) bar graphs show CCR5 expression on CD4+CD95+ T cells in controls, second bar ...
Tissues were collected as described in the legend for Fig 10. The specific markers used to distingui...
(A, B) Number (left) and frequency (right) of CD44hi DbLT359 tetramer+ CD8 T cells in brain (A) and ...
<p>T cells (CD3<sup>+</sup> cells) were immunostained and counted (absolute number, n) in coronal sl...
<div><h3>Background</h3><p>Hypoxic ischemia (HI) is an important cause of neonatal brain injury and ...
(A) Representative histogram of CD103+ and CD103- DbLT359 tetramer+ CD8 T cells from brain and splee...