IL-6 production is increased in cardiac fibrosis induced by Ang II.

<p>(<b>A</b>) Immunohistochemical analysis of IL-6 production (brown) in ventricles of mice (n = 6 per group) after saline or Ang II infusion. (<b>B</b>) Western blot analysis for IL-6 expression in the hearts of WT mice. (<b>C</b>) Systolic blood pressure (SBP) was measured and echocardiography was performed at day 7 after Ang II infusion. Error bars represent mean±SEM. *<i>P</i><0.05; ***<i>P</i><0.001. Scale bars: 50 µm.