Echocardiographic evaluation of 3 to 4 month-old Wild type and Fabry Knock Out (KO) mice.

<p>Data represent the means ± SE. Statistical significance was determined by unpaired, two-tailed <i>t</i>-test: *P<0.05: **P<0.01.</p><p>Abbreviations: LA, left atrium; LV, left ventricle; LV EDD, left ventricular end diastolic diameter; Vcfc, velocity of shortening of circumferential fibers; Sa, Spw: maximal systolic velocity of the mitral annulus and posterior wall; IVRT: isovolumic relaxation time; Ea and Epw: maximal diastolic velocity of the mitral annulus and posterior wall; E, maximal velocity of LV inflow.