<p>Tumor samples from wtFKBP5 SU86 or shFKBP5 SU86 xenografts were prepared and analyzed for phosphorylation of Akt and downstream signaling molecules by Western blot analysis.</p
[[abstract]]FK506-binding proteins (FKBPs) are intracellular receptors for FK506 and rapamycin, immu...
<p>(A) Dose-dependent effect of T315 on the viability of LNCaP, PC-3, and MDA-MB-468 (468) cells in ...
The HMG-box protein 1 (HBP1) is a transcriptional regulator and a potential tumor suppressor that co...
SummaryAkt is a central regulator of cell growth. Its activity can be negatively regulated by the ph...
<div><p>We have recently shown that the immunophilin FKBP5 (also known as FKBP51) is a scaffolding p...
We have recently shown that the immunophilin FKBP5 (also known as FKBP51) is a scaffolding protein t...
We have recently shown that the immunophilin FKBP5 (also known as FKBP51) is a scaffolding protein t...
<div><p>A. Western blots for Akt with a focus on phosphorylated Akt on Ser473 and Thr308. HEK293 cel...
[[abstract]]Nuclear exclusion of the forkhead transcription factor FOXO3a by protein kinase Akt cont...
<p>(A) Tumor samples were assessed by IHC for p-AKT(S473) and p-PRAS40(T246). Veh: Vehicle. (B) p-AK...
<p>A bar diagram showing independence of phosphorylation of Akt at T308 (▪) and S473 (□) in kinase a...
AbstractNuclear exclusion of the forkhead transcription factor FOXO3a by protein kinase Akt contribu...
The serine-threonine kinase AKT, also known as protein kinase B (PKB), was identified in 1977 as the...
<p>Mice bearing subcutaneous wtFKBP5 SU86 and shFKBP5 SU86 tumors entered the study when tumors reac...
The FK506-binding protein 51 (FKBP51) is an Hsp90-associated co-chaperone which regulates steroid re...
[[abstract]]FK506-binding proteins (FKBPs) are intracellular receptors for FK506 and rapamycin, immu...
<p>(A) Dose-dependent effect of T315 on the viability of LNCaP, PC-3, and MDA-MB-468 (468) cells in ...
The HMG-box protein 1 (HBP1) is a transcriptional regulator and a potential tumor suppressor that co...
SummaryAkt is a central regulator of cell growth. Its activity can be negatively regulated by the ph...
<div><p>We have recently shown that the immunophilin FKBP5 (also known as FKBP51) is a scaffolding p...
We have recently shown that the immunophilin FKBP5 (also known as FKBP51) is a scaffolding protein t...
We have recently shown that the immunophilin FKBP5 (also known as FKBP51) is a scaffolding protein t...
<div><p>A. Western blots for Akt with a focus on phosphorylated Akt on Ser473 and Thr308. HEK293 cel...
[[abstract]]Nuclear exclusion of the forkhead transcription factor FOXO3a by protein kinase Akt cont...
<p>(A) Tumor samples were assessed by IHC for p-AKT(S473) and p-PRAS40(T246). Veh: Vehicle. (B) p-AK...
<p>A bar diagram showing independence of phosphorylation of Akt at T308 (▪) and S473 (□) in kinase a...
AbstractNuclear exclusion of the forkhead transcription factor FOXO3a by protein kinase Akt contribu...
The serine-threonine kinase AKT, also known as protein kinase B (PKB), was identified in 1977 as the...
<p>Mice bearing subcutaneous wtFKBP5 SU86 and shFKBP5 SU86 tumors entered the study when tumors reac...
The FK506-binding protein 51 (FKBP51) is an Hsp90-associated co-chaperone which regulates steroid re...
[[abstract]]FK506-binding proteins (FKBPs) are intracellular receptors for FK506 and rapamycin, immu...
<p>(A) Dose-dependent effect of T315 on the viability of LNCaP, PC-3, and MDA-MB-468 (468) cells in ...
The HMG-box protein 1 (HBP1) is a transcriptional regulator and a potential tumor suppressor that co...
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