Counter-regulation of gene expression by AAT or PM as determined by DNA microarrays of normal (NOR), diabetic (DIA) and AAT or PM treated PLNs and fat tissues from NOD mice.

<p>The genes were identified in a supervised analysis using an absolute fold change of 2 and P value<0.05. <b>A</b>) Hierarchical cluster analysis of top transcripts that are differentially expressed in PLNs extracted from diabetic mice vs. normal non-diabetic control mice. <b>B</b>) Cluster analysis illustrating the transcripts that are significantly counter-regulated by AAT treatment in PLNs. The columns represent the samples and rows represent the genes. Gene expression is shown with pseudocolor scale (−1 to 1) with red denoting high gene expression levels and green denoting low gene expression levels of genes.