<p>Phosphosite Plus database was searched for tyrosine phosphorylation within SH3 domains. The identified SH3 domains were aligned using ClustalW. Human sequences are shown except those depicted with <b>_m</b>, which come form mouse. All the sequences were obtained using SMART server. Names of proteins according to UniProt database are situated on the left including the domain range if there are more then one SH3 domains within a protein. Alignment is numbered at the top. Phosphorylated tyrosines are highlighted in red. Orthologous and paralogous sequences with identical phosphosites are not included.</p
We have developed a procedure to predict the peptide binding specificity of an SH3 domain from its s...
We have developed a procedure to predict the peptide binding specificity of an SH3 domain from its s...
<p>Protein sequences from mouse IRS-2 (NP_001074681.1), human IRS-2 (NP_003740.2), mouse IRS-1 (NP_0...
<div><h3>Background</h3><p>SH3 domains are eukaryotic protein domains that participate in a plethora...
Reversible phosphorylation maintained by protein kinases and phosphatases is an integral part of int...
<p>(A) Alignment of protein sequences of the human ITSNs SH3 domains. The alignment was generated us...
Top and bottom left, serum amyloid A and α-2HS-glycoprotein / fetuin A sequence alignments for homo ...
grantor: University of TorontoTo take full advantage of the current wealth of protein sequ...
Understanding the impact of protein phosphorylation is very important for the formation of dynamic b...
<p>A. Cas family protein sequences aligned at the PRALINE website. Shown is the region of alignment ...
Intricate molecular signalling within cellular environment is manifested through phosphorylation of ...
The overall function of a multi-domain protein is determined by the functional and structural interp...
<p>For each SH3 domain, the overlap between discovered motifs and known SH3 binding sites was measur...
Tyrosine phosphatases play an important role in cellular signalling and networking that is antagonis...
<p>a) Sequence alignment of murine intersectin SH3 domains A through E. The observed secondary struc...
We have developed a procedure to predict the peptide binding specificity of an SH3 domain from its s...
We have developed a procedure to predict the peptide binding specificity of an SH3 domain from its s...
<p>Protein sequences from mouse IRS-2 (NP_001074681.1), human IRS-2 (NP_003740.2), mouse IRS-1 (NP_0...
<div><h3>Background</h3><p>SH3 domains are eukaryotic protein domains that participate in a plethora...
Reversible phosphorylation maintained by protein kinases and phosphatases is an integral part of int...
<p>(A) Alignment of protein sequences of the human ITSNs SH3 domains. The alignment was generated us...
Top and bottom left, serum amyloid A and α-2HS-glycoprotein / fetuin A sequence alignments for homo ...
grantor: University of TorontoTo take full advantage of the current wealth of protein sequ...
Understanding the impact of protein phosphorylation is very important for the formation of dynamic b...
<p>A. Cas family protein sequences aligned at the PRALINE website. Shown is the region of alignment ...
Intricate molecular signalling within cellular environment is manifested through phosphorylation of ...
The overall function of a multi-domain protein is determined by the functional and structural interp...
<p>For each SH3 domain, the overlap between discovered motifs and known SH3 binding sites was measur...
Tyrosine phosphatases play an important role in cellular signalling and networking that is antagonis...
<p>a) Sequence alignment of murine intersectin SH3 domains A through E. The observed secondary struc...
We have developed a procedure to predict the peptide binding specificity of an SH3 domain from its s...
We have developed a procedure to predict the peptide binding specificity of an SH3 domain from its s...
<p>Protein sequences from mouse IRS-2 (NP_001074681.1), human IRS-2 (NP_003740.2), mouse IRS-1 (NP_0...