Behavior of adolescent rats pre-exposed to saline or valproic acid (VPA) during gestation.

<p>Animals were tested for social interactions, play behaviors, spontaneous locomotor activity, and self-grooming. Rats showed lower social interaction (t-test t₂₀ = 2.1, p = 0.04) and greater locomotor activity (t-test t₂₀ = 2.1, p = 0.03). No differences were observed with play behavior and self-grooming. However, play attacks to the nape were significantly lower in VPA compared with SAL animals (t₂₀ = 2.1, p = 0.04; data not shown). All data shown as mean ± standard error. *Significantly different from SAL (two-tailed t-test, p<0.05).