Polymorphisms in <i>MOH1</i> and <i>CDC6</i> are prevalent in <i>C. glabrata</i> clinical isolates with <i>FKS2-</i>mediated echinocandin resistance.

<p>Genomic regions harbouring the 9 non-synonymous mutations uncovered in isolate G relative to isolate A were sequenced by Sanger sequencing in 10 unrelated <i>C. glabrata</i> echinocandin-resistant clinical isolates containing the resistance mutation <i>FKS2</i> T1987C/Fks2 S663P. Synonymous mutations are in black font; non-synonymous mutations are in red with amino acid mutations listed in parentheses. Sequences were compared to both the reference CBS138 sequence as well as a control sample sequenced from the laboratory isolate BG2 (CgLC1272).