The best estimated protective SNP combinations on the occurrence of breast cancer as determined by IPSO.

*<p>The SNP combinations on the occurrence of breast cancer are significantly different (<i>p value</i><0.05). Sen.; Sensitivity; Spe., specificity; PPV, positive predictive value; NPV, negative predictive value. The meanings of the SNP and genotype numbers are provided in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0037018#pone-0037018-t003" target="_blank">Table 3</a>. For example, barcode SNPs (4-19)-genotype (1-1) is [rs3020314-CC]-[rs500760-AA]; SNPs (4, 19, 23) with genotype 1-1-2; [rs3020314-CC]-[rs500760-AA]-[rs2017591-TC].