Maturation of innate immune function in PNG infants.

<p>Whole blood samples from PNG infants aged 1–3 months (n = 18, <i>white bars</i>), 4–6 months (n = 18, <i>light grey bars</i>), 7–12 months (n = 21, <i>dark grey bars</i>) or 13–18 months (n = 10, <i>black bars</i>) were stimulated with TLR (LTA; PolyIC; LPS; Gardiquimod) and NLR (iE-DAP; MDP) ligands, and Alum alone or with LPS co-stimulation (denoted by ♦). Presented are the geometric means and 95% confidence intervals (pg/mL) for each age group for background-adjusted cytokine responses. Significance level is indicated where p<0.05.