<p>**p<0.01, ***p<0.001 (A). (B) Representative western blot confirming up regulation of ATP1A3 in rat striatal neurons treated with indicated concentrations of METH for 24 h as compared to controls. (C) Bar graphs showing significant increase in ATP1A3 expression post METH treatment versus control. Data represented as Mean ± SEM of three independent experiments. *p<0.05.</p
<p>(A) Western blot analysis showing pERK levels at different time points after exposure to sub-leth...
<p>Microglial cells were incubated with Meth, and the level of Kv1.3, Kv1.5 proteins were detected b...
<p><i>Top panels:</i> Representative immunoblots show levels of mGluR2/3 and mGluR7 protein in total...
<p>(M – METH, I – Interferon-γ, T – TNF-α). Bar graphs showing significant increase in ATP1A3 expres...
<p>*p<0.05, **p<0.01 versus control, #p<0.05 versus cytokine ± METH treatment.</p
<p>(A) but SP600125 or SB203580 do not (B, C). Data represented as Mean ± SEM of three independent e...
<p>(A) and with synaptic marker synaptophysin (B). DAPI was used to stain cell nucleus. Cells treate...
<p>Time course of gene expression, determined by qRTPCR, in striatum from mice treated with 10 mg/kg...
<p>Primary rat striatal neurons (8 DIV) stained for levels and distribution of PDIA3 after 250 µM ME...
<p>(A). Fold changes relative to sham-control group in the level of ATP, ADP or ADP/ATP ratio in sam...
<p>(A) Representative immunoblots show expression of TH, DAT and 5-HTT protein levels in the striatu...
<p><b>A-B:</b> Effects of METH on GLUT3 (45 kDa) protein levels in human neurons. Bar graph shows th...
<p>Representative Western blot analyses show that the METH self-administering rats had increased GFA...
<p>(A) METH injection reduced THir in +/+ and +/− mice following one time binge METH exposure (1X ME...
<p>Mice were sacrificed 15 minutes after a single dose of either METH (3 mg/kg, s.c.) or vehicle (10...
<p>(A) Western blot analysis showing pERK levels at different time points after exposure to sub-leth...
<p>Microglial cells were incubated with Meth, and the level of Kv1.3, Kv1.5 proteins were detected b...
<p><i>Top panels:</i> Representative immunoblots show levels of mGluR2/3 and mGluR7 protein in total...
<p>(M – METH, I – Interferon-γ, T – TNF-α). Bar graphs showing significant increase in ATP1A3 expres...
<p>*p<0.05, **p<0.01 versus control, #p<0.05 versus cytokine ± METH treatment.</p
<p>(A) but SP600125 or SB203580 do not (B, C). Data represented as Mean ± SEM of three independent e...
<p>(A) and with synaptic marker synaptophysin (B). DAPI was used to stain cell nucleus. Cells treate...
<p>Time course of gene expression, determined by qRTPCR, in striatum from mice treated with 10 mg/kg...
<p>Primary rat striatal neurons (8 DIV) stained for levels and distribution of PDIA3 after 250 µM ME...
<p>(A). Fold changes relative to sham-control group in the level of ATP, ADP or ADP/ATP ratio in sam...
<p>(A) Representative immunoblots show expression of TH, DAT and 5-HTT protein levels in the striatu...
<p><b>A-B:</b> Effects of METH on GLUT3 (45 kDa) protein levels in human neurons. Bar graph shows th...
<p>Representative Western blot analyses show that the METH self-administering rats had increased GFA...
<p>(A) METH injection reduced THir in +/+ and +/− mice following one time binge METH exposure (1X ME...
<p>Mice were sacrificed 15 minutes after a single dose of either METH (3 mg/kg, s.c.) or vehicle (10...
<p>(A) Western blot analysis showing pERK levels at different time points after exposure to sub-leth...
<p>Microglial cells were incubated with Meth, and the level of Kv1.3, Kv1.5 proteins were detected b...
<p><i>Top panels:</i> Representative immunoblots show levels of mGluR2/3 and mGluR7 protein in total...