Circular Diagram of the <i>M. bovis</i> HB0801 Genome Structure.

<p>The <i>dna</i>A gene is at position zero. Starting from the outside, the first circle shows the genome length (units in Mb); the second and the third circles show the locations of the predicted CDSs on the plus and minus strands, respectively, which were color-coded by COG categories (gold for translation, ribosomal structure and biogenesis; orange for RNA processing and modification; light orange for transcription; dark orange for DNA replication, recombination and repair; antique white for cell division and chromosome partitioning; pink for defense mechanisms; red for signal transduction mechanisms; peach for cell envelope biogenesis and outer membrane; deep pink for intracellular trafficking, secretion and vesicular transport; pale green for post-translational modification, protein turnover and chaperones; royal blue for energy production and conversion; blue for carbohydrate transport and metabolism; dodger blue for amino acid transport and metabolism; sky blue for nucleotide transport and metabolism; light blue for coenzyme metabolism; cyan for lipid metabolism; medium purple for inorganic ion transport and metabolism; aquamarine for secondary metabolites biosynthesis, transport and catabolism; and gray for unknown function); the fourth circle shows tRNAs (violet) and rRNAs (red); the fifth circle shows the centered GC (G+C) content of each CDS (red: above mean and blue: below mean); and the sixth circle shows the GC (G+C) skew plot.