<p>(A) Sanger sequencing chromatograms representing confimed TET1 variants. (B) Schematic representation of TET1 protein structure with indication of all novel TET1 variants detected in this study. Variants detected in cell lines are depicted above the TET1 protein, variants detected in leukemia patient samples are below the TET1 protein. Non-somatic variants are indicated with an asterisk.</p
This is an open access article distributed under the Creative Commons Attribution License.TET2 is in...
<p>Of the filtered 41 candidates, 21 variants were confirmed by Sanger sequencing. Two examples are ...
<p>(A) Schematic representation of ATM protein domains showing location of somatic mutations in ATM ...
<p>(A) Sanger sequencing chromatograms corresponding to confirmed JAK2/JAK3 variants. (B) Domain str...
<p>(A and B) Visualization of chromosomal breakpoint junctions in diagnostic leukemia cells of ETP-A...
Disease alleles that activate signal trans-duction are common in myeloid malignan-cies; however, the...
(A) The tet(A)wt and tet(A)ΔtetR variants of tet(A), including a schematic of the regulation of tetA...
Copyright © 2014 Maŕıa Hernández-Sánchez et al. This is an open access article distributed under ...
(A). Structure of TET1 protein. TET1 protein contains a CXXC domain and a catalytic domain (CD) incl...
TET2 is involved in a variety of hematopoietic malignancies, mainly in myeloid malignancies. Most mu...
<p>NGS, Next Generation Sequencing; Mut cases, cases with any mutation; Del Ex19, deletion in exon 1...
<p>(A) Sanger sequencing chromatograms showing confirmed SPRY4 variants. (B) Domain structure of the...
(A) Occurrence of tet(A) alleles in 3 collections of E. coli. Black lines represent alleles containi...
<p>(A) Expression levels of Tet1 and Tet3, but not Tet2, correlate with C to G somatic mutation rate...
<p>A) Chromatogram showing relative intensities of each base pair after Sanger sequencing in both th...
This is an open access article distributed under the Creative Commons Attribution License.TET2 is in...
<p>Of the filtered 41 candidates, 21 variants were confirmed by Sanger sequencing. Two examples are ...
<p>(A) Schematic representation of ATM protein domains showing location of somatic mutations in ATM ...
<p>(A) Sanger sequencing chromatograms corresponding to confirmed JAK2/JAK3 variants. (B) Domain str...
<p>(A and B) Visualization of chromosomal breakpoint junctions in diagnostic leukemia cells of ETP-A...
Disease alleles that activate signal trans-duction are common in myeloid malignan-cies; however, the...
(A) The tet(A)wt and tet(A)ΔtetR variants of tet(A), including a schematic of the regulation of tetA...
Copyright © 2014 Maŕıa Hernández-Sánchez et al. This is an open access article distributed under ...
(A). Structure of TET1 protein. TET1 protein contains a CXXC domain and a catalytic domain (CD) incl...
TET2 is involved in a variety of hematopoietic malignancies, mainly in myeloid malignancies. Most mu...
<p>NGS, Next Generation Sequencing; Mut cases, cases with any mutation; Del Ex19, deletion in exon 1...
<p>(A) Sanger sequencing chromatograms showing confirmed SPRY4 variants. (B) Domain structure of the...
(A) Occurrence of tet(A) alleles in 3 collections of E. coli. Black lines represent alleles containi...
<p>(A) Expression levels of Tet1 and Tet3, but not Tet2, correlate with C to G somatic mutation rate...
<p>A) Chromatogram showing relative intensities of each base pair after Sanger sequencing in both th...
This is an open access article distributed under the Creative Commons Attribution License.TET2 is in...
<p>Of the filtered 41 candidates, 21 variants were confirmed by Sanger sequencing. Two examples are ...
<p>(A) Schematic representation of ATM protein domains showing location of somatic mutations in ATM ...