Kinetics of intracellular cytokine/chemokine production following stimulation of PBMC with <i>S</i>. Typhi-infected autologous B-LCL.

<p>Intracellular cytokine/chemokine production is shown as the percentage of positive cells. Responses are expressed as net values with day 0 subtracted to normalize for differences in base-line responses to <i>S</i>. Typhi in different volunteers. A) CD8+ T_EM cells for volunteer 53 s B) CD8+ T_EMRA cells for volunteer 53 s C) CD8+ T_EM cells for volunteer 54 s D) CD8+ T_EMRA cells for volunteer 54 s E) CD8+ T_EM cells for volunteer 50 s F) CD8+ T_EMRA cells for volunteer 50 s. Increases of >0.5% cytokine positive cells over uninfected targets were found to be consistently statistically significant (P<0.01) by chi-square analyses. * MIP-1b not measured.