Effect of <i>Bc</i>-SMase on the infection with <i>B. cereus</i> or <i>B. subtilis.</i>

<p>Mice received various concentrations of <i>Bc</i>-SMase and <i>B. cereus</i> (ATCC21928, 5×10⁷ CFU/mouse). A) Mice were monitored every five hours after the injection. The duration of the experiment was set at 100 h. ○, <i>B. cereus</i>; □, 1.0 µg <i>Bc</i>-SMase; △, 5.0 µg <i>Bc</i>-SMase; ▴, 0.1 µg <i>Bc</i>-SMase + <i>B. cereus</i>; •, 1.0 µg <i>Bc</i>-SMase + <i>B. cereus</i>; ▪, 5.0 µg <i>Bc</i>-SMase + <i>B. cereus</i>. B) <i>B. cereus</i> in blood was cultured on Luria broth agar plates. Values represent the mean ± SEM; <i>n</i> = 5 independent experiments.