Plot of the functional classifications of all upregulated and downregulated proteins in the biofilm compared to the planktonic growth form.

<p>All of the tabulated proteins met a 1.5-fold cutoff threshold for differential expression, with quantitation p-values <0.05. Functional role assignments for the <i>N. gonorrhoeae</i> proteins were downloaded from the JCVI-CMR website (<a href="http://cmr.jcvi.org/tigr-scripts/CMR/CmrHomePage.cgi" target="_blank">http://cmr.jcvi.org/tigr-scripts/CMR/CmrHomePage.cgi</a>). In a few cases where functional role assignments were not available, the <i>N. gonorrhoeae</i> proteins were given tentative assignments in the present study after conducting BLAST and KEGG orthology searches (see Supplementary <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0038303#pone.0038303.s009" target="_blank">Tables S5</a> and <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0038303#pone.0038303.s010" target="_blank">S6</a> for details).