<p>The rate of sweeps per unit map length , plotted against the baseline rate, . The solid line shows , the dashed curve shows the additive approximation given by the solution to Eq. (8) , and the points show simulation results. Different kinds of points represent different values of ; as predicted by the scaling argument, depends on only through . until interference becomes strong at , after which increases only slowly. While the simulated values of continue to increase above Eq. (8) 's “upper limit” of 0.5, they do so only very slowly, remaining even for . (Note that even when Eq. (8) underestimates , it appears that our scaling argument still holds.) Selection and map length are held constant at and while population size and mut...
<p>(A, C, E): Mean fitness, relative to maximum attainable with perfect heritability. (B, D, F): Mea...
<div><p>In large populations, many beneficial mutations may be simultaneously available and may comp...
<p>The figure shows the effect on parameter estimation when the mutation rate is varied along the ge...
<p>The figure shows data from simulated populations with mutation supply . The total genetic map len...
<p>The scaled probability of fixation of a beneficial mutation, , plotted as a function of the stren...
<p>Simulation results for scaled mean probability of fixation for mutations with exponentially dist...
<p>Points show the beginnings of simulated selective sweeps. The distribution over time and map leng...
<p>Solid curves and points show the probability of fixation of a mutation as a function of its selec...
<p>For each combination of <i>U</i> ( = 0.1, 0.3, and 0.5) and <i>s</i> ( = 0.01 and 0.1), simulatio...
A) Speed of fixation of selective sweep mutations. B) Dynamics of fixations that occur after the new...
<p>Here is the dominance parameter, as described in the section entitled Fitness Calculation. The s...
<p>Fixation probability of a new mutation with advantage occurring after an interfering sweep with ...
<p>Simulation results are illustrated for populations under complete selfing (<i>S</i> = 1; broken l...
(a) Probability Phard,s(2) of observing a single allele in a pair drawn from a subrange of size Ls f...
<p>For all five parameter combinations, we use <i>c</i> = 10<sup>−11</sup>. Most simulations reach e...
<p>(A, C, E): Mean fitness, relative to maximum attainable with perfect heritability. (B, D, F): Mea...
<div><p>In large populations, many beneficial mutations may be simultaneously available and may comp...
<p>The figure shows the effect on parameter estimation when the mutation rate is varied along the ge...
<p>The figure shows data from simulated populations with mutation supply . The total genetic map len...
<p>The scaled probability of fixation of a beneficial mutation, , plotted as a function of the stren...
<p>Simulation results for scaled mean probability of fixation for mutations with exponentially dist...
<p>Points show the beginnings of simulated selective sweeps. The distribution over time and map leng...
<p>Solid curves and points show the probability of fixation of a mutation as a function of its selec...
<p>For each combination of <i>U</i> ( = 0.1, 0.3, and 0.5) and <i>s</i> ( = 0.01 and 0.1), simulatio...
A) Speed of fixation of selective sweep mutations. B) Dynamics of fixations that occur after the new...
<p>Here is the dominance parameter, as described in the section entitled Fitness Calculation. The s...
<p>Fixation probability of a new mutation with advantage occurring after an interfering sweep with ...
<p>Simulation results are illustrated for populations under complete selfing (<i>S</i> = 1; broken l...
(a) Probability Phard,s(2) of observing a single allele in a pair drawn from a subrange of size Ls f...
<p>For all five parameter combinations, we use <i>c</i> = 10<sup>−11</sup>. Most simulations reach e...
<p>(A, C, E): Mean fitness, relative to maximum attainable with perfect heritability. (B, D, F): Mea...
<div><p>In large populations, many beneficial mutations may be simultaneously available and may comp...
<p>The figure shows the effect on parameter estimation when the mutation rate is varied along the ge...