<p><i>RPE:</i> the number of Reads Per Exon after adjusting the length of the exon and the overall sequencing depth per sample. <i>P<sub>HQR</sub></i>: the Proportion of High-Quality Reads for each exon. Each point represents an exon. The grey points represent all the exons in one sample. The red points indicate the distribution of the 13<sup>th</sup> exon of the gene <i>CDC27</i> in all 36 samples, and purple points indicate the distribution of the 42<sup>nd</sup> exon of the gene <i>MLL3</i> in all 36 samples, both of which are representative spurious genes and failed to be validated by experiments. The vertical dash line is set <i>RPE</i> = 1.5 and the horizontal dash line is set <i>P<sub>HQR</sub></i> = 0.4.</p
<p>(A) Detection threshold determination. False positive and negative rates for the detection of gen...
<p>The gene expression values from three different RNA-seq data processing methods (MMSEQ, read coun...
<p>(<b>A</b>) The expression profiles of 326 EUR samples for 94 genes in the gene set. The expressio...
<p>*. Percent positive is calculated based on [# of positive/total # of samples tested]. For each sa...
<div><p>Assessing criteria that identify candidate spurious genes in <i>S. cerevisiae,</i> using a r...
<p>A random distribution would be represented by an equal representation of <i>p</i>-values across t...
<p>A) The overall mapping and counting workflow. B) A hypothetical gene, its two isoforms and read c...
<p>The top panels show visualization of read alignment in good (a) and bad (b) conditions using the ...
When identifying differentially expressed genes between two conditions using human population RNA-se...
Background: Thousands of genes in a genomewide data set are tested against some null hypothesis, for...
In recent years, RNA-seq has become a very competitive alternative to microarrays. In RNA-seq experi...
<p>Schematic overview of our comparison strategy: our “Mouse RPE signature genes” dataset and “Human...
<p>The RNA-seq data are from the MAQC dataset, containing two types of biological samples: human bra...
AbstractFisher’s exact test is widely used in biomedical research, particularly in genomic profile a...
Below the histogram, two lanes containing light-blue bars indicate the genes that are part of the pu...
<p>(A) Detection threshold determination. False positive and negative rates for the detection of gen...
<p>The gene expression values from three different RNA-seq data processing methods (MMSEQ, read coun...
<p>(<b>A</b>) The expression profiles of 326 EUR samples for 94 genes in the gene set. The expressio...
<p>*. Percent positive is calculated based on [# of positive/total # of samples tested]. For each sa...
<div><p>Assessing criteria that identify candidate spurious genes in <i>S. cerevisiae,</i> using a r...
<p>A random distribution would be represented by an equal representation of <i>p</i>-values across t...
<p>A) The overall mapping and counting workflow. B) A hypothetical gene, its two isoforms and read c...
<p>The top panels show visualization of read alignment in good (a) and bad (b) conditions using the ...
When identifying differentially expressed genes between two conditions using human population RNA-se...
Background: Thousands of genes in a genomewide data set are tested against some null hypothesis, for...
In recent years, RNA-seq has become a very competitive alternative to microarrays. In RNA-seq experi...
<p>Schematic overview of our comparison strategy: our “Mouse RPE signature genes” dataset and “Human...
<p>The RNA-seq data are from the MAQC dataset, containing two types of biological samples: human bra...
AbstractFisher’s exact test is widely used in biomedical research, particularly in genomic profile a...
Below the histogram, two lanes containing light-blue bars indicate the genes that are part of the pu...
<p>(A) Detection threshold determination. False positive and negative rates for the detection of gen...
<p>The gene expression values from three different RNA-seq data processing methods (MMSEQ, read coun...
<p>(<b>A</b>) The expression profiles of 326 EUR samples for 94 genes in the gene set. The expressio...