<p>The data was expressed as mean±SEM and IFN-γ SFCs per epitope peptide, with the SFCs values from the negative control subtracted. The data from 5 self-limited and 6 chronic HCV infection subjects was included. Triplicate wells of every peptide in the same experiments were used. <b>A</b>. IFN-γ SFCs from the predicted peptides in self-limited HCV infection. <b>B</b>. IFN-γ SFCs from the predicted peptides in chronic HCV infection. “<b><sup>★</sup></b>” stands for positive epitope peptide, which had the strongest stimulatory function of IFN-γ secretion in self-limited HCV infection and defined by >25 SFCs/2×10<sup>5</sup> PBMCs after subtracting the negative control SFCs value.</p
It has been reported that monoclonal antibodies (MAbs) to the E1E2 glycoproteins may have the potent...
<p>PBMC were stimulated in triplicates with two sets of seven pooled overlapping 15-mer HCV genotype...
<p><b>(A)</b> Direct <i>ex vivo</i> IFN-γ ELISpot assay was performed to examine HCV-specific T cell...
<p>The data was expressed as mean±SEM. The data from 5 subjects for every group was included. Tripli...
<p>The data was expressed as mean±SEM, IL-2, IFN-γ, IL-4, and IL-10 concentration in the supernatant...
<p>(A) Representative flow cytometry plots showing intracellular IFN-γ staining of a CTL line expose...
<p>(A) Representative flow cytometry plots showing intracellular IFN-γ staining with CD8+ T cells fr...
<p>The data was expressed as mean±SEM. The data from 5 subjects from every group was included. Tripl...
<p>A: number of SFC in negative control was substracted.</p><p>B: number of SFC was <3-fold the mean...
<p>Whole PBMC or PBMC depleted of either CD4<sup>+</sup> or CD8<sup>+</sup> T cells from 17 HCMV ser...
<p>Exogenous peptide in the presence of sera at a dilution resulting in approximately 50% inhibition...
<p>PBMC isolated from Egyptians with chronic or resolved HCV infection were stimulated in triplicate...
<p>Antiviral efficacy (white bars) and functional avidity (filled circles) of CTL lines, derived fro...
Proliferation of antigen-specific CD4/CD8 T-cells, in response to stimulation using peptide pools, h...
It has been reported that monoclonal antibodies (MAbs) to the E1E2 glycoproteins may have the potent...
It has been reported that monoclonal antibodies (MAbs) to the E1E2 glycoproteins may have the potent...
<p>PBMC were stimulated in triplicates with two sets of seven pooled overlapping 15-mer HCV genotype...
<p><b>(A)</b> Direct <i>ex vivo</i> IFN-γ ELISpot assay was performed to examine HCV-specific T cell...
<p>The data was expressed as mean±SEM. The data from 5 subjects for every group was included. Tripli...
<p>The data was expressed as mean±SEM, IL-2, IFN-γ, IL-4, and IL-10 concentration in the supernatant...
<p>(A) Representative flow cytometry plots showing intracellular IFN-γ staining of a CTL line expose...
<p>(A) Representative flow cytometry plots showing intracellular IFN-γ staining with CD8+ T cells fr...
<p>The data was expressed as mean±SEM. The data from 5 subjects from every group was included. Tripl...
<p>A: number of SFC in negative control was substracted.</p><p>B: number of SFC was <3-fold the mean...
<p>Whole PBMC or PBMC depleted of either CD4<sup>+</sup> or CD8<sup>+</sup> T cells from 17 HCMV ser...
<p>Exogenous peptide in the presence of sera at a dilution resulting in approximately 50% inhibition...
<p>PBMC isolated from Egyptians with chronic or resolved HCV infection were stimulated in triplicate...
<p>Antiviral efficacy (white bars) and functional avidity (filled circles) of CTL lines, derived fro...
Proliferation of antigen-specific CD4/CD8 T-cells, in response to stimulation using peptide pools, h...
It has been reported that monoclonal antibodies (MAbs) to the E1E2 glycoproteins may have the potent...
It has been reported that monoclonal antibodies (MAbs) to the E1E2 glycoproteins may have the potent...
<p>PBMC were stimulated in triplicates with two sets of seven pooled overlapping 15-mer HCV genotype...
<p><b>(A)</b> Direct <i>ex vivo</i> IFN-γ ELISpot assay was performed to examine HCV-specific T cell...