The frequency of IFN-γ-producing CTLs from PBMCs cocultured with mDC loaded with peptides.

<p>The data was expressed as mean±SEM. The data from 5 subjects for every group was included. Triplicate wells of every peptide in the same experiment were used. The single peptides include 4 previously reported epitope peptides (E2 (723–731), NS3 (1073–1081), NS3 (1585–1593), and NS5b (2594–2602)), 7 predicted peptides and HLA-A2-restricted CTL HBV envelope epitope peptide (WLSLLVPFV) as an unrelated peptide control. The epitope peptide mixtures (mix1∼mix14) contains 2 to 6 single epitope peptides in each mixture. <b>A</b>. IFN-γ SFCs induced by single peptide in self-limited and chronic HCV infection. <b>B</b>. IFN-γ SFCs induced by multiple epitope peptide mixtures in self-limited and chronic HCV infection; *P<0.05.