<p>Binding affinities (<i>K</i><sub>d</sub>) of Ang II, olmesartan, R239470 and R794847 to AT<sub>1</sub> wild-type (WT) and mutant receptors.</p
<p>*The values are expressed as the mean ± S.E (n = 2 to 5 experiments in duplicate), and the experi...
To identify residues of the rat AT(1A) angiotensin II receptor involved with signal transduction and...
International audienceEarlier studies with Mas protooncogene, a member of the G-protein-coupled rece...
<p>Binding affinities (<i>K</i><sub>d</sub>) of Ang II, olmesartan, R239470 and R794847 to AT<sub>1<...
<p>Binding affinities (<i>K</i><sub>d</sub>) of Ang II and R compounds to AT<sub>1</sub> wild-type (...
<p>Binding affinities (K<sub>D</sub>) of the single mutants for MD2 were measured from the associati...
<p><b><i>A</i></b>, shows the theoretical binding curves (with the apparent binding constant <i>K<su...
Homology modeling of the structure of the AT, receptor, based on the high resolution rhodopsin cryst...
<p>Binding inhibition curves for <sup>125</sup>I-HEAT (200 pM) binding to WT (0.2 µg, black), F187<s...
AbstractMutational analysis based on pharmacological differences between mammalian and amphibian ang...
<p>Ki values were obtained by simultaneous analysis of at least 3 independent competition experiment...
<p>Fold-increase indicates the ratio of binding affinities between the mutants and wild-type decoy r...
Earlier studies with Mas protooncogene, a member of the G-protein-coupled receptor family, have prop...
<p><b>a</b>, Basal, agonist induced and antagonist-inhibited cAMP accumulation was measured on cos 7...
a<p>Mutations to the wild type <i>algD</i> binding site are notated by the bolded nucleotides in eac...
<p>*The values are expressed as the mean ± S.E (n = 2 to 5 experiments in duplicate), and the experi...
To identify residues of the rat AT(1A) angiotensin II receptor involved with signal transduction and...
International audienceEarlier studies with Mas protooncogene, a member of the G-protein-coupled rece...
<p>Binding affinities (<i>K</i><sub>d</sub>) of Ang II, olmesartan, R239470 and R794847 to AT<sub>1<...
<p>Binding affinities (<i>K</i><sub>d</sub>) of Ang II and R compounds to AT<sub>1</sub> wild-type (...
<p>Binding affinities (K<sub>D</sub>) of the single mutants for MD2 were measured from the associati...
<p><b><i>A</i></b>, shows the theoretical binding curves (with the apparent binding constant <i>K<su...
Homology modeling of the structure of the AT, receptor, based on the high resolution rhodopsin cryst...
<p>Binding inhibition curves for <sup>125</sup>I-HEAT (200 pM) binding to WT (0.2 µg, black), F187<s...
AbstractMutational analysis based on pharmacological differences between mammalian and amphibian ang...
<p>Ki values were obtained by simultaneous analysis of at least 3 independent competition experiment...
<p>Fold-increase indicates the ratio of binding affinities between the mutants and wild-type decoy r...
Earlier studies with Mas protooncogene, a member of the G-protein-coupled receptor family, have prop...
<p><b>a</b>, Basal, agonist induced and antagonist-inhibited cAMP accumulation was measured on cos 7...
a<p>Mutations to the wild type <i>algD</i> binding site are notated by the bolded nucleotides in eac...
<p>*The values are expressed as the mean ± S.E (n = 2 to 5 experiments in duplicate), and the experi...
To identify residues of the rat AT(1A) angiotensin II receptor involved with signal transduction and...
International audienceEarlier studies with Mas protooncogene, a member of the G-protein-coupled rece...