<p>The oral mucosa, salivary glands, CLN and NALT were harvested from BLT mice and stained with the appropriate antibodies to verify the presence of human leukocytes (CD45<sup>+</sup>) including dendritic cells (CD11c<sup>+</sup>), macrophages (CD68<sup>+</sup>), B cells (CD20<sup>+</sup>), T cells (CD3<sup>+</sup>), CD4<sup>+</sup> T cells (CD4<sup>+</sup>) and CD8<sup>+</sup> T cells (CD8<sup>+</sup>). Positive cells appear brown. Scale bars = 100 µm.</p
<p>(A) Schematic representation of the strategic methodology for engrafting human CD34<sup>+</sup> c...
<p>Peripheral blood, spleen, lymph nodes, and bone marrow were harvested at GvHD development in Hu-P...
<p>The (A) percentage and (B) total number of hCD45<sup>+</sup> cells in the bone marrow (BM), thymu...
<p>The esophagus, stomach and duodenum were harvested from BLT mice for IHC analysis to determine if...
<p>Immunohistochemical analysis of the vagina, ectocervix, endocervix, and uterus of female BLT mice...
The humanized bone marrow-liver-thymus (BLT) mouse model harbors a nearly complete human immune syst...
<p>Tissue sections of lymphoid organs (spleen, lymph node, and thymus) from humanized Rag1<sup>−/−</...
Periodontitis is a chronic inflammatory response to a microbial biofilm that destroys bone and soft ...
<p>(A) Flow cytometric analyses were performed to determine the level of human CD45<sup>+</sup> cell...
INTRODUCTION: Immunodeficient mice engrafted with human immune systems support studies of human hema...
<p>(A) Absolute number of human cells in lymph nodes, bone marrow and spleens of group 1 and group 7...
INTRODUCTION: Immunodeficient mice engrafted with human immune systems support studies of human hema...
<p>Two groups of NSG mice (n = 5 each) received 50×10<sup>3</sup> bone marrow derived CD34 positive ...
We established a humanized mouse model incorporating FLT3-ligand (FLT3-L) administration after hemat...
Immunodeficient mice engrafted with human immune systems provide an exciting model to study human im...
<p>(A) Schematic representation of the strategic methodology for engrafting human CD34<sup>+</sup> c...
<p>Peripheral blood, spleen, lymph nodes, and bone marrow were harvested at GvHD development in Hu-P...
<p>The (A) percentage and (B) total number of hCD45<sup>+</sup> cells in the bone marrow (BM), thymu...
<p>The esophagus, stomach and duodenum were harvested from BLT mice for IHC analysis to determine if...
<p>Immunohistochemical analysis of the vagina, ectocervix, endocervix, and uterus of female BLT mice...
The humanized bone marrow-liver-thymus (BLT) mouse model harbors a nearly complete human immune syst...
<p>Tissue sections of lymphoid organs (spleen, lymph node, and thymus) from humanized Rag1<sup>−/−</...
Periodontitis is a chronic inflammatory response to a microbial biofilm that destroys bone and soft ...
<p>(A) Flow cytometric analyses were performed to determine the level of human CD45<sup>+</sup> cell...
INTRODUCTION: Immunodeficient mice engrafted with human immune systems support studies of human hema...
<p>(A) Absolute number of human cells in lymph nodes, bone marrow and spleens of group 1 and group 7...
INTRODUCTION: Immunodeficient mice engrafted with human immune systems support studies of human hema...
<p>Two groups of NSG mice (n = 5 each) received 50×10<sup>3</sup> bone marrow derived CD34 positive ...
We established a humanized mouse model incorporating FLT3-ligand (FLT3-L) administration after hemat...
Immunodeficient mice engrafted with human immune systems provide an exciting model to study human im...
<p>(A) Schematic representation of the strategic methodology for engrafting human CD34<sup>+</sup> c...
<p>Peripheral blood, spleen, lymph nodes, and bone marrow were harvested at GvHD development in Hu-P...
<p>The (A) percentage and (B) total number of hCD45<sup>+</sup> cells in the bone marrow (BM), thymu...