<div><p>Liver regeneration (LR) after partial hepatectomy (PH) involves the proliferation and apoptosis of hepatocytes, and microRNAs have been shown to post-transcriptionally regulate genes involved in the regulation of these processes. To explore the role of miR-127 during LR, the expression patterns of miR-127 and its related proteins were investigated. MiR-127 was introduced into a rat liver cell line to examine its effects on the potential target genes <em>Bcl6</em> and <em>Setd8</em>, and functional studies were undertaken. We discovered that <em>miR-127</em> was down-regulated and inversely correlated with the expression of Bcl6 and Setd8 at 24 hours after PH, a time at which hypermethylation of the promoter region of the miR-127 gen...
MicroRNAs are a class of small regulatory RNAs that modulate a variety of biological processes, incl...
The extraordinary ability of liver cells to proliferate underlies the remarkable regenerative capaci...
<p>(<b>A</b>) Cell cycle of BRL-3A cells transfected with miR-127 mimics (miR-127) or miRNA negative...
Liver regeneration (LR) after partial hepatectomy (PH) involves the proliferation and apoptosis of h...
Liver regeneration (LR) after partial hepatectomy (PH) involves the proliferation and apoptosis of h...
<p>. (<b>A</b>) Scatter plot of miRNA expression in PH rats versus SH rats at 3 h post surgery quant...
microRNAs (miRNAs) are critically involved in liver regeneration (LR). miR-125a-5p (miR-125a) is a t...
The ability of the liver to regenerate and restore mass limits the increasing mortality rate due to ...
BACKGROUND: Inadequate liver regeneration (LR) is still an unsolved problem in major liver resection...
<div><h3>Background</h3><p>Inadequate liver regeneration (LR) is still an unsolved problem in major ...
The liver is one of the few organs that have the capacity to regenerate in response to injury. We ca...
Liver regeneration after partial hepatectomy (PH) is a highly orchestrated biological process in whi...
BACKGROUND.: The molecular mechanisms underlying the growth of small size grafts and the remaining l...
BACKGROUND: MicroRNAs are a class of small regulatory RNAs that modulate a variety of biological pro...
Altered expression of microRNAs (miRNAs) has been reported in diverse human cancers; however, the do...
MicroRNAs are a class of small regulatory RNAs that modulate a variety of biological processes, incl...
The extraordinary ability of liver cells to proliferate underlies the remarkable regenerative capaci...
<p>(<b>A</b>) Cell cycle of BRL-3A cells transfected with miR-127 mimics (miR-127) or miRNA negative...
Liver regeneration (LR) after partial hepatectomy (PH) involves the proliferation and apoptosis of h...
Liver regeneration (LR) after partial hepatectomy (PH) involves the proliferation and apoptosis of h...
<p>. (<b>A</b>) Scatter plot of miRNA expression in PH rats versus SH rats at 3 h post surgery quant...
microRNAs (miRNAs) are critically involved in liver regeneration (LR). miR-125a-5p (miR-125a) is a t...
The ability of the liver to regenerate and restore mass limits the increasing mortality rate due to ...
BACKGROUND: Inadequate liver regeneration (LR) is still an unsolved problem in major liver resection...
<div><h3>Background</h3><p>Inadequate liver regeneration (LR) is still an unsolved problem in major ...
The liver is one of the few organs that have the capacity to regenerate in response to injury. We ca...
Liver regeneration after partial hepatectomy (PH) is a highly orchestrated biological process in whi...
BACKGROUND.: The molecular mechanisms underlying the growth of small size grafts and the remaining l...
BACKGROUND: MicroRNAs are a class of small regulatory RNAs that modulate a variety of biological pro...
Altered expression of microRNAs (miRNAs) has been reported in diverse human cancers; however, the do...
MicroRNAs are a class of small regulatory RNAs that modulate a variety of biological processes, incl...
The extraordinary ability of liver cells to proliferate underlies the remarkable regenerative capaci...
<p>(<b>A</b>) Cell cycle of BRL-3A cells transfected with miR-127 mimics (miR-127) or miRNA negative...