Myofibroblast fibronectin, shed external lamina, and intercellular junction.

<p><b>A</b>) There is copious actin (A) with prominent dense bodies (long red arrows) in this large pleomorphic myofibroblast. The nucleus is also large and irregular. Note the electron dense fibronectin (long black arrows). The ECM is loose and contains shed external lamina (short red arrows). Case 32, original magnification 5,000×. <b>B</b>) The cell has two prominent visible cytoplasmic extensions and is shedding strips of external lamina (short red arrows) into a loose stroma of granular-fibrillar ECM, with no banded collagen. Dense bodies (long red arrow), actin (A) and RER are present within the cell. Case 26, original magnification 5,000×. Inset: A non-specific junction (JXT) joins two MF. Actin (A) is present with very prominent dense bodies (long red arrows). Case 13, original magnification 10,000×.