The phenotypes of wild-type, <i>Del(9)olt1Pas, oltSH</i> and <i>oltNH</i> mutant mice.

<p>The phenotype of wild-type (Wt), <i>Del(9)olt1Pas</i> (<i>olt</i>) homozygotes, <i>oltSH</i> and <i>oltNH</i> mice during hair follicle morphogenesis (P11 and P14) and the first hair cycle (P24 and P28). The + and – indicate the wild-type and mutant allele, respectively. The genotypes given below the images were determined by genomic PCR assays as described in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0039203#pone-0039203-g002" target="_blank">Figure 2</a> B. Mutants of the <i>oltSH</i> phenotype have a reduced dorsal pelage on day P11 and P14 (A and B), which becomes very sparse during the first hair cycle (C and D). Ventrally, <i>oltSH</i> mutants show total alopecia (E to H) compared to homozygous <i>Del(9)olt1Pas</i> mice (F to H), in which the coat is predominantly reduced in the medial femoral and inguinal region (arrows in F, G, and H). <i>oltNH</i> mutants have no pelage.