Phylogenetic relationships among the Drosophila HP1 genes.

<p>We constructed phylogenetic trees generated in BEAST (see <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1002729#s4" target="_blank">Materials and Methods</a>) using codon-based alignments of the Chromodomain (A) or Chromoshadow domain (B) based on a log-normal relaxed molecular clock <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1002729#pgen.1002729-Drummond2" target="_blank">[58]</a>. For clarity, we only present posterior probabilities for major clade relationships rather than between orthologs of the same gene (complete trees with all posterior probability support values indicated can be found in supplemental data (<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1002729#pgen.1002729.s005" target="_blank">Figure S5A, S5B</a>)). In most instances orthologs grouped together with a high degree of support (exceptions, including the <i>HP1Lcsd</i> genes are discussed in the main text). Genes that are shaded gray refer to partial HP1s that encode either a chromodomain (in A) or shadow domains (in B) only. Scale bar refers to the expected number of substitutions per site.