<p>(<b>A,B</b>) Correlation between the viral load (HCV-RNA copies) and CD8<sup>+</sup>pentamer<sup>+</sup> T<sub>EM</sub> cells producing IFN-γ (A) or IL-17 (B) in response to apoptotic epitopes in patients with acute HCV infection experiencing chronic infection or infection resolution. (<b>C,D</b>)Correlation between ALT and CD8<sup>+</sup>pentamer<sup>+</sup> T<sub>EM</sub> cells producing IFN-γ(C) or IL-17 (D) in response to apoptotic epitopes in patients with acute HCV infection experiencing chronic infection or infection resolution.</p
<p>Serum (A,B) and liver levels (C–E) of IL-28 (A-protein; C-mRNA), IL-29 (B-protein, D-mRNA), and I...
CD8+ T cells specific to caspase-cleaved antigens derived from apoptotic T cells represent a princip...
Hepatitis C virus (HCV) is a major cause of chronic hepatitis worldwide. The immune mechanisms that ...
<p>(<b>A</b>) Kinetics of plasma HCV-RNA and ALT levels until 15–24 months from clinical onset of in...
<p>(<b>A,B</b>) Representative flow cytometry analyses of PBMCs from patients with acute HCV infecti...
<p>(<b>A</b>) PBMCs from three independent patients with acute HCV infection were stained with mAb t...
<p>CD25-depleted PBMC from patients with acute HCV infection (SR or CI) were stained with CFSE and s...
CD8+ T lymphocyte responses are important in the clearance of viral infections. In chronic infection...
<p>(<b>A</b>) Level of expression of Tim-3 defines differential exhaustion statuses of HCV-specific ...
Aim: We investigated the relationship between the magnitude of comprehensive hepatitis C virus (HCV)...
Caspase-dependent cleavage of antigens associated with apoptotic cells plays a prominent role in the...
<p>(<b>A</b>) Representative experiment in which PBMCs from a patient with acute HCV infection were ...
<div><p>Caspase-dependent cleavage of antigens associated with apoptotic cells plays a prominent rol...
<p>(<b>A</b>) Representative decay plot of the natural logarithm of the normalized fluorescence vers...
<p>(<b>A</b>) Increased plasma levels of IL-21 during acute resolving HCV. Plasma levels of the Th17...
<p>Serum (A,B) and liver levels (C–E) of IL-28 (A-protein; C-mRNA), IL-29 (B-protein, D-mRNA), and I...
CD8+ T cells specific to caspase-cleaved antigens derived from apoptotic T cells represent a princip...
Hepatitis C virus (HCV) is a major cause of chronic hepatitis worldwide. The immune mechanisms that ...
<p>(<b>A</b>) Kinetics of plasma HCV-RNA and ALT levels until 15–24 months from clinical onset of in...
<p>(<b>A,B</b>) Representative flow cytometry analyses of PBMCs from patients with acute HCV infecti...
<p>(<b>A</b>) PBMCs from three independent patients with acute HCV infection were stained with mAb t...
<p>CD25-depleted PBMC from patients with acute HCV infection (SR or CI) were stained with CFSE and s...
CD8+ T lymphocyte responses are important in the clearance of viral infections. In chronic infection...
<p>(<b>A</b>) Level of expression of Tim-3 defines differential exhaustion statuses of HCV-specific ...
Aim: We investigated the relationship between the magnitude of comprehensive hepatitis C virus (HCV)...
Caspase-dependent cleavage of antigens associated with apoptotic cells plays a prominent role in the...
<p>(<b>A</b>) Representative experiment in which PBMCs from a patient with acute HCV infection were ...
<div><p>Caspase-dependent cleavage of antigens associated with apoptotic cells plays a prominent rol...
<p>(<b>A</b>) Representative decay plot of the natural logarithm of the normalized fluorescence vers...
<p>(<b>A</b>) Increased plasma levels of IL-21 during acute resolving HCV. Plasma levels of the Th17...
<p>Serum (A,B) and liver levels (C–E) of IL-28 (A-protein; C-mRNA), IL-29 (B-protein, D-mRNA), and I...
CD8+ T cells specific to caspase-cleaved antigens derived from apoptotic T cells represent a princip...
Hepatitis C virus (HCV) is a major cause of chronic hepatitis worldwide. The immune mechanisms that ...