OCR and ECAR after overnight exposure to 18-carbon fatty acids of differing saturation.

<p>A) Oleate, stearate, linoleate, or linolenate did not alter OCR compared to control cells unexposed to fatty acid. Data represent mean ± SEM values at the time points indicated (n = 12–14 for each data point). B) ECAR determined simultaneously with OCR in panel A. Linolenate, the most highly unsaturated species, enhanced ECAR. C) Quantitative data (mean ± SEM ) comparing fatty acid effects on ECAR during the conditions indicated (Ant + Rot = antimycin A plus rotenone). D) OCR versus ECAR (mean ± SEM for both parameters) E) ECAR to OCR ratios according to fatty acid treatment (mean ± SEM). * p<0.05 or ** p<0.01 compared to control.