The usage of VH family genes by human anti-HIV-1 and non-HIV-1 mAbs.

<p>These mAbs were produced from single B cells derived from one HIV infected individual and are compared to antibodies with undefined specificities produced from single B cells of four healthy control subjects <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0039534#pone.0039534-Tiller2" target="_blank">[21]</a>. The preferential usage of the VH3 versus VH1 family genes by non-HIV-1 mAbs compared controls and significantly increased usage of VH1 family genes of anti-HIV-1 versus non-HIV-1 mAbs was determined by the Chi-Squared test. NS – not significant.