RBC velocities along the vessel network of brain AVMs in mice.

<p><b>A</b>, Low-magnification TPLSM image of cortical vasculature in Notch4* mouse model with the blood plasma labeled by Texas Red-dextran. <b>A’</b>, Diagram of the vascular network from image (A) with arteries shown in red, veins in blue, and shunts in purple. Artery-to-vein pathways are highlighted and labeled with arrowheads to indicate the direction of flow and specific locations of velocity and diameter measurements. Bold numbers represent average center-axis velocity in units of mm/s and italic numbers represent diameter in units of µm corresponding to the adjacent arrowheads. <b>B</b>, Representative analyses in a subset of vessels (v1–v4) from panels (A’).