Kinase knockdown has minimal effect on non-cancer cells.

<p>The relative effect of two independent shRNAs per kinase on cell growth in LHS (A) and MCF10A (B) cells. CyQuant Assay measured DNA content as a surrogate for cell number 7 days after shRNA transduction. n = 2 for LHS cells and n = 3 for MCF10A cells. Cell growth was compared to pLKO control and the values were averaged across biological replicates. Error bars represent standard error of the mean.