Enrichment of functional interactions for protein-protein interactions.

<p>(A), (B) and (C) correspond to enrichment analysis of protein-protein interactions (PPIs) in the posterior probabilities for associations belonging to the , and component, respectively. In each one of the three figures, the upper panel shows ranked phenotypes by a pink curve and the positions of PPIs in the ranked phenotypes, while the lower panel illustrates the running sum scores of GSEA (Gene Set Enrichment Analysis) random walks <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1002566#pcbi.1002566-Subramanian1" target="_blank">[45]</a>.