Radiation therapy of tumors in NFκB1 knockout mice.

<p>a) Wild-type (wt) or NFκB1^−/− C57BL/6 mice were challenged with 2×10⁵ Panc02 <i>s.c.</i> in the right leg and mice received 3 daily doses of 20 Gy focal radiation to the leg beginning on day 14 (RT) or were left untreated (NT).Tumor leg diameter was measured 3× per week. b) Survival curves of mice in a replicate experiment treated as in a) where mice were euthanized at a leg diameter exceeding 12 mm. c) Proportion of tumors growing following s.c. injection of 3LL or Panc02 in NFκB1^−/− naïve mice or NFκB1^−/− mice that were cured of their primary tumor with radiation therapy (RT).