<p>Whole mount hybridization in situ of BMP target genes Tbx2 and Tbx3 in stage 33/34 embryos injected unilaterally with 90 ng SPC7 morpholino. Injected sides are shown to the right. (A, B) Lateral view of embryos showing Tbx2 expression was lost in the eye on the MO-injected side only (NR, neural retina; CG, cranial ganglion; OV, otic vesicle; BA, branchial arches; FN, frontonasal process). (C, D) Lateral view of stage 33/34 embryos showing a similar result for Tbx3.</p
<p>A, phenotypes generated by increasing doses of <i>tbx5a</i> mRNA. The percentage of embryos with ...
<div><p>(A–C) MOs directed against 14-3-3η. (A) Control MO; embryos develop normally.</p><p>(B) Embr...
BMPs have been shown to play a role in neural tube development particularly as dorsalizing factors. ...
<p>(A-D) Whole mount hybridization in situ of embryos injected unilaterally with 90 ng SPC7 morpholi...
<p>(A,B) Whole mount ISH for <i>gfp</i> in <i>Tg(Bre:gfp)</i> embryos, lateral views, anterior to th...
(a) tbx5b expression in the eyes (asterisk) and lateral plate mesoderm (arrow) of 21 hpf embryos. (b...
<p>(A, B) Otolith morphology observed in 2 dpf untreated embryos. (C, D) Absence of otoliths, in oth...
(A-B) Wild-type embryos were exposed to different inhibitors from bud stage to the 17-somite stage a...
<p>ISH of <i>bmp2/4</i> and pSmad immunostaining in control and DM-treated embryos at the LG (A, tre...
<p>(A, B) Embryos injected unilaterally with antisense SPC7-MO at the two cell (A) or four cell stag...
<p>(<b>A</b>) Lateral view of 14 hpf embryo. Lateral-dorsal view of 20 hpf embryo (<b>B</b>) hindbra...
(A) bmp2b expression during early somite stages. In situ hybridization of bmp2b in whole mount embry...
<p>Whole-mount <i>in situ</i> hybridization for <i>Tbx3</i> in wt (A, B) and <i>Gli3<sup>xt/xt</sup>...
(A-B) In situ hybridization analysis of the expression of foxa1 (A), nkx2.7, nkx2.3, and pdgfαa (B) ...
<p>(A) Hoechst (cyan) and Histone H3[p Ser10] (magenta) staining reveals mitotic cells of a represen...
<p>A, phenotypes generated by increasing doses of <i>tbx5a</i> mRNA. The percentage of embryos with ...
<div><p>(A–C) MOs directed against 14-3-3η. (A) Control MO; embryos develop normally.</p><p>(B) Embr...
BMPs have been shown to play a role in neural tube development particularly as dorsalizing factors. ...
<p>(A-D) Whole mount hybridization in situ of embryos injected unilaterally with 90 ng SPC7 morpholi...
<p>(A,B) Whole mount ISH for <i>gfp</i> in <i>Tg(Bre:gfp)</i> embryos, lateral views, anterior to th...
(a) tbx5b expression in the eyes (asterisk) and lateral plate mesoderm (arrow) of 21 hpf embryos. (b...
<p>(A, B) Otolith morphology observed in 2 dpf untreated embryos. (C, D) Absence of otoliths, in oth...
(A-B) Wild-type embryos were exposed to different inhibitors from bud stage to the 17-somite stage a...
<p>ISH of <i>bmp2/4</i> and pSmad immunostaining in control and DM-treated embryos at the LG (A, tre...
<p>(A, B) Embryos injected unilaterally with antisense SPC7-MO at the two cell (A) or four cell stag...
<p>(<b>A</b>) Lateral view of 14 hpf embryo. Lateral-dorsal view of 20 hpf embryo (<b>B</b>) hindbra...
(A) bmp2b expression during early somite stages. In situ hybridization of bmp2b in whole mount embry...
<p>Whole-mount <i>in situ</i> hybridization for <i>Tbx3</i> in wt (A, B) and <i>Gli3<sup>xt/xt</sup>...
(A-B) In situ hybridization analysis of the expression of foxa1 (A), nkx2.7, nkx2.3, and pdgfαa (B) ...
<p>(A) Hoechst (cyan) and Histone H3[p Ser10] (magenta) staining reveals mitotic cells of a represen...
<p>A, phenotypes generated by increasing doses of <i>tbx5a</i> mRNA. The percentage of embryos with ...
<div><p>(A–C) MOs directed against 14-3-3η. (A) Control MO; embryos develop normally.</p><p>(B) Embr...
BMPs have been shown to play a role in neural tube development particularly as dorsalizing factors. ...