Hierarchical clustering of all cytokines and transcription factors genes.

<p>(A) Based on annotation for bovine DGE profiles, we identified 138 unique cytokine genes and their related genes. Normalized intensity values of genes (rows) and their H3K27me3 modifications were ordered using Centroid Spearman Rank Correlation and hierarchical clustering in Cluster3.0 software. The dendrogram showed the similarity (distance) of mRNA expression levels and H3K27me3 modifications of genes and was divided into sub-trees as distinguished from different colors. Arrays (columns) were grouped by four different individuals. Yellow and blue colors reflect the high and low intensities, respectively. (B) Based on annotation for bovine DGE profiles, 178 unique transcription factors and related genes were identified. The heatmap and the hierarchical cluster were generated as above described.