Measure of IL-8 secretion by fibroblasts co-incubated with different strains of <i>B. burgdorferi</i> ss.

<p>(A-C) IL-8 secretion of fibroblasts stimulated by different concentrations of <i>Borrelia</i> N40, Pbre, 1408 at MOI of 100∶1 (100B), 10∶1 (10B), and 1∶1 (1B) at 24 hours. (D-F) Kinetic studies of IL-8 secretions in the three strains. NEG: unstimulated fibroblasts. (A-F) Each bar shows the mean ± SDs of triplicate values and is representative of three independent experiments. ***P<0.001; **P<0.01; and *P<0.05 compared between stimulated and unstimulated cells.