BORIS-dependent DNA demethylation of <i>SBSN</i> CpG island.

<p>DNA was isolated from H358 cells transfected with BORIS expressing vector and induced by indicated doxycycline concentrations. DNA was treated by bisulfite, purified and used for QMSP with <i>SBSN</i>-specific primers and probes at <i>SBSN</i> as described in methods. Values are normalized to beta-actin unmethylated control. (*, p-value <0.03).