Heterogeneity in the expression of 35 proteins assessed by reverse-phase-protein-arrays.

<p>There was considerable intratumoral heterogeneity in the expression of all 35 proteins analyzed, and even more pronounced variation amongst different patients.</p><p>Intratumoral, differences between individual samples of the same primary tumor or between individual lymph node metastases from the same patient.</p><p>CV, coefficient of variation given as percentage; Primary tumor, whole tumor including central, peripheral, and intermediate zone; LN, lymph node; Total, total case including all primary tumor and lymph node samples.</p><p>Phospho, all phosphorylated proteins combined; Non-phospho, all non-phosphorylated proteins combined;</p><p>Overall, all 35 proteins combined.