<p>Human washed platelets were seeded on fibrinogen-coated cover slips in the presence of BF066 at different concentrations, PI3-kinase inhibitor LY294002 (100 nM) or DMSO. Platelets were stained with FITC-phalloidin and observed under a 40× objective with magnification of 5.</p
In this study, we report BF066, a novel adenine derivative, inhibits platelet activation and thrombo...
<p>Platelets were deposited on fibrinogen-coated coverslips in a live-cell chamber for 45 min and vi...
BACKGROUND: We recently demonstrated that platelet aggregation occurred in fibrinogen-deficient mice...
<p>A) The structures of BF066, BF061 and AR-C69931MX. B) BF066 concentration-dependently inhibited A...
<p><b>(A)</b> Washed human platelets spread on BSA- or IgG-coated coverslips for 30 minutes in the p...
<p>BF066 concentration-dependently inhibited activity of PDE extracted from human platelets. A) Repr...
Glycoprotein VI, a major platelet activation receptor for collagen and fibrin, is considered a parti...
AbstractFocal adhesion kinase (FAK) is activated in human platelets downstream of integrins, e.g. αI...
<p>(A) Exposure of PS by R-6G labeled platelets (red) in the presence of either (i) FK633 (30 µM), (...
<p>Platelets (1.2×10<sup>8</sup> platelets/ml) were pre-incubated or not with ODQ (10 µM, 3 min) and...
<p>Spreading of washed platelets from Cdc42<sup>+/+</sup> and Cdc42<sup>−/−</sup> mice on CRP or fib...
<p>Washed human platelets with or without treatment with U46619 (0.25μM) in the presence or absence ...
Glycoprotein VI (GPVI), a platelet collagen receptor, is crucial in mediating atherothrombosis. Besi...
<div><p>In this study, we report BF066, a novel adenine derivative, inhibits platelet activation and...
<p>(A) Gel filtered human platelets (2×10<sup>7</sup>/mL) were preincubated with S14161 (2.5 µM, 5 µ...
In this study, we report BF066, a novel adenine derivative, inhibits platelet activation and thrombo...
<p>Platelets were deposited on fibrinogen-coated coverslips in a live-cell chamber for 45 min and vi...
BACKGROUND: We recently demonstrated that platelet aggregation occurred in fibrinogen-deficient mice...
<p>A) The structures of BF066, BF061 and AR-C69931MX. B) BF066 concentration-dependently inhibited A...
<p><b>(A)</b> Washed human platelets spread on BSA- or IgG-coated coverslips for 30 minutes in the p...
<p>BF066 concentration-dependently inhibited activity of PDE extracted from human platelets. A) Repr...
Glycoprotein VI, a major platelet activation receptor for collagen and fibrin, is considered a parti...
AbstractFocal adhesion kinase (FAK) is activated in human platelets downstream of integrins, e.g. αI...
<p>(A) Exposure of PS by R-6G labeled platelets (red) in the presence of either (i) FK633 (30 µM), (...
<p>Platelets (1.2×10<sup>8</sup> platelets/ml) were pre-incubated or not with ODQ (10 µM, 3 min) and...
<p>Spreading of washed platelets from Cdc42<sup>+/+</sup> and Cdc42<sup>−/−</sup> mice on CRP or fib...
<p>Washed human platelets with or without treatment with U46619 (0.25μM) in the presence or absence ...
Glycoprotein VI (GPVI), a platelet collagen receptor, is crucial in mediating atherothrombosis. Besi...
<div><p>In this study, we report BF066, a novel adenine derivative, inhibits platelet activation and...
<p>(A) Gel filtered human platelets (2×10<sup>7</sup>/mL) were preincubated with S14161 (2.5 µM, 5 µ...
In this study, we report BF066, a novel adenine derivative, inhibits platelet activation and thrombo...
<p>Platelets were deposited on fibrinogen-coated coverslips in a live-cell chamber for 45 min and vi...
BACKGROUND: We recently demonstrated that platelet aggregation occurred in fibrinogen-deficient mice...