Results of PCA on Rho crystal structures.

<p>Conformer plot of available Rho GTPase crystal structures projected in the planes defined by the two most significant principal components (termed PC1 and PC2, see insert). Crystallographic GTP structures are colored red, GDP green, and nucleotide free gray. Inset: Eigenvalue spectrum: results obtained from diagonalisation of the covariance matrix of aligned atom coordinates from the Rho crystal structures. The magnitude of each eigenvalue is expressed as the percentage of the total variance (mean square fluctuation) captured by the corresponding eigenvector. Labels indicate the cumulative sum of the proportion of the total variance accounted for in all preceding eigenvectors.