Expression of T-box transcription factors T-bet and Eomes after infections with rVSV_GP and <i>rListeria_GP33</i> infection.

<p>P14.WT, P14.IL-12RKO, P14.IFNARKO or P14.DOKO T cells were transferred into B6 mice followed by infection with <b><i>A,</i></b> rVSV_GP, or <b><i>B,</i></b><i> rListeria_GP33</i>. Expression of T-bet and Eomes was analyzed in the spleen on day 5 after infection. Histograms show intracellular expression of T-bet or Eomes in P14.WT (black line), P14.DOKO (red line) and naïve P14 CD8 T cells (filled curve) directly <i>ex vivo</i>. Percentages of T-bet or Eomes positive P14 T cells of total P14 T cells are indicated (middle panels). Mean fluorescence intensity (MFI) of T-bet or Eomes expression of P14 T cells is shown (right panels). p<0,01. Results are representative of two independent experiments.