<p>Down-regulation of eEF-2K by siRNA enhances the efficacy of paclitaxel-induced (2 nM) inhibition of colony formation in highly aggressive and metastatic MDA-MB-231 breast cancer cells. (<b>A</b>) Cell colonies stained with crystal violet and (<b>B</b>) Quantification of colony formation represented graphically.</p
<p>(A) Percentage viability of HeLa clones (control: Vector 6 and Vector 8; ILK overexpressing: ILK ...
OBJECTIVE:To identify the proteins involved the compensatory adaptive response to paclitaxel in ovar...
In this study, we investigated whether selective signal pathways were associated with eribulin acti...
<p>(<b>A</b>) Western blot analysis demonstrated that knockdown of eEF-2K in doxorubicin-treated MDA...
<div><p>Eukaryotic elongation factor 2 kinase (eEF-2K), through its phosphorylation of elongation fa...
Eukaryotic elongation factor 2 kinase (eEF-2K), through its phosphorylation of elongation factor 2 (...
<p>Depletion of eEF-2K by siRNA inhibits invasion (A), while overexpression of eEF-2K increases inva...
<p><i>A</i>. H1299 cells were transiently transfected with 200 pmol control, E2F3a, or E2F3b siRNA a...
Purpose: Most patients with ovarian cancer receive paclitaxel chemotherapy, but less than half respo...
<p>(<b>a</b>) Visible morphological changes from “cobblestone”-like to “fibroblast”-like cells was o...
The CDK/Rb/E2F pathway is commonly disrupted in lung cancer, and thus, it is predicted that blocking...
<p>Cells were treated with 3.2 or 4 µM MSA, 10 nM paclitaxel, or the combinations for 72 hr. Live ce...
<p>Cell lysates were subjected to Western blotting. Relative protein levels were quantified by densi...
Cancer League of Colorado [BCTR0707449, AWD-102888]; Colorado CTSA grant [UL1TR000154]; NCATS/NIH; N...
<p>(A) Effect of knockdown of <i>RAP1A</i> and <i>STAT3</i> expression by siRNA on cell viability in...
<p>(A) Percentage viability of HeLa clones (control: Vector 6 and Vector 8; ILK overexpressing: ILK ...
OBJECTIVE:To identify the proteins involved the compensatory adaptive response to paclitaxel in ovar...
In this study, we investigated whether selective signal pathways were associated with eribulin acti...
<p>(<b>A</b>) Western blot analysis demonstrated that knockdown of eEF-2K in doxorubicin-treated MDA...
<div><p>Eukaryotic elongation factor 2 kinase (eEF-2K), through its phosphorylation of elongation fa...
Eukaryotic elongation factor 2 kinase (eEF-2K), through its phosphorylation of elongation factor 2 (...
<p>Depletion of eEF-2K by siRNA inhibits invasion (A), while overexpression of eEF-2K increases inva...
<p><i>A</i>. H1299 cells were transiently transfected with 200 pmol control, E2F3a, or E2F3b siRNA a...
Purpose: Most patients with ovarian cancer receive paclitaxel chemotherapy, but less than half respo...
<p>(<b>a</b>) Visible morphological changes from “cobblestone”-like to “fibroblast”-like cells was o...
The CDK/Rb/E2F pathway is commonly disrupted in lung cancer, and thus, it is predicted that blocking...
<p>Cells were treated with 3.2 or 4 µM MSA, 10 nM paclitaxel, or the combinations for 72 hr. Live ce...
<p>Cell lysates were subjected to Western blotting. Relative protein levels were quantified by densi...
Cancer League of Colorado [BCTR0707449, AWD-102888]; Colorado CTSA grant [UL1TR000154]; NCATS/NIH; N...
<p>(A) Effect of knockdown of <i>RAP1A</i> and <i>STAT3</i> expression by siRNA on cell viability in...
<p>(A) Percentage viability of HeLa clones (control: Vector 6 and Vector 8; ILK overexpressing: ILK ...
OBJECTIVE:To identify the proteins involved the compensatory adaptive response to paclitaxel in ovar...
In this study, we investigated whether selective signal pathways were associated with eribulin acti...