Flow cytometric analyses of human immune cells invading the infected footpad.

<p>(A) Infected footpad (3×10⁶<i>L. major</i>) of a humanized mouse is shown. (B) The invasion of human B cells (CD19) and human T cells (CD3) to the site of infection were determined (n = 3). (C) T cells were further characterized for CD4⁺ T helper and CD8⁺ cytotoxic T cell subsets and (D) their naïve (CD27⁺CD45RA⁺) and memory (CD27⁺CD45RA⁻) phenotype. Significances between groups were analyzed using Student's t test (* = p<0.05; ** = p<0.01, n = 3). Error bars represent means ± SEM (standard error of the mean).