<p>Symbols represent mean ± SE (n = 7) of aspartate aminotransferase (AST, ▪), alanine aminotransferase (ALT, □), total bilirubin (•), direct bilirubin (0), blood urea nitrogen (BUN, ▴) and albumin (◊); monkeys were treated with DB844 at 6 mg/kg×14 days, from 28–41 days post infection.</p
<p>Monkeys confirmed to have second stage HAT were administered DB868 orally, beginning at 28 days p...
<p>Key: d, day;DPI, days post-infection; DPT, days post-treatment (post-last drug dose of DB829 or D...
<p>Monkeys confirmed to have second stage HAT were administered DB829 intramuscularly, beginning at ...
<p>DB868 was administered orally at 10 mg/kg/day (n = 4) or 30 mg/kg/day (n = 4) for 10 days, day −9...
<p>DB868 was administered orally at 10 mg/kg/day (n = 4) or 30 mg/kg/day (n = 4) for 10 days, day −9...
<p>Symbols and error bars represent geometric means and SEs, respectively, for DB844 (△) and DB820 (...
<p>The monkeys (n = 4) were administered DB868 orally at 30 mg/kg/day for 10 days, day −9 to day 0 p...
<p>Monkeys were infected with <i>T. b. rhodesiense</i> KETRI 2537 and upon confirmation of onset of ...
<p>Symbols and error bars represent means and SEs, respectively, of 7 animals; monkeys were treated ...
<p>Fold change in serum levels and correlation with viral genome copy number of alanine aminotransfe...
<p>The monkeys confirmed to have first stage HAT were administered DB868 orally, beginning at 7 days...
<p>Key: RBC = red blood cells; WBC = White blood cells; g/dl = grams/decilitre; fl = femtolitres; p-...
<p>Starting at 7 days post-infection with <i>T. b. rhodesiense</i> KETRI 2537, monkeys confirmed to ...
<p>Alanine aminotransferase (ALT), glucose, and total bilirubin concentrations in the serum of mock ...
<p>Clinical chemistries were performed on serum using a Piccolo Point-Of-Care instrument. Clinical c...
<p>Monkeys confirmed to have second stage HAT were administered DB868 orally, beginning at 28 days p...
<p>Key: d, day;DPI, days post-infection; DPT, days post-treatment (post-last drug dose of DB829 or D...
<p>Monkeys confirmed to have second stage HAT were administered DB829 intramuscularly, beginning at ...
<p>DB868 was administered orally at 10 mg/kg/day (n = 4) or 30 mg/kg/day (n = 4) for 10 days, day −9...
<p>DB868 was administered orally at 10 mg/kg/day (n = 4) or 30 mg/kg/day (n = 4) for 10 days, day −9...
<p>Symbols and error bars represent geometric means and SEs, respectively, for DB844 (△) and DB820 (...
<p>The monkeys (n = 4) were administered DB868 orally at 30 mg/kg/day for 10 days, day −9 to day 0 p...
<p>Monkeys were infected with <i>T. b. rhodesiense</i> KETRI 2537 and upon confirmation of onset of ...
<p>Symbols and error bars represent means and SEs, respectively, of 7 animals; monkeys were treated ...
<p>Fold change in serum levels and correlation with viral genome copy number of alanine aminotransfe...
<p>The monkeys confirmed to have first stage HAT were administered DB868 orally, beginning at 7 days...
<p>Key: RBC = red blood cells; WBC = White blood cells; g/dl = grams/decilitre; fl = femtolitres; p-...
<p>Starting at 7 days post-infection with <i>T. b. rhodesiense</i> KETRI 2537, monkeys confirmed to ...
<p>Alanine aminotransferase (ALT), glucose, and total bilirubin concentrations in the serum of mock ...
<p>Clinical chemistries were performed on serum using a Piccolo Point-Of-Care instrument. Clinical c...
<p>Monkeys confirmed to have second stage HAT were administered DB868 orally, beginning at 28 days p...
<p>Key: d, day;DPI, days post-infection; DPT, days post-treatment (post-last drug dose of DB829 or D...
<p>Monkeys confirmed to have second stage HAT were administered DB829 intramuscularly, beginning at ...